Notes: December 19, 2022 -- The Board determined to set the reverse stock split ratio at 1-for-100 (the “Reverse Stock Split”). The Reverse Stock Split will become effective as of 12:01 a.m., Eastern Time on December 20, 2022 (the “Effective Time”), pursuant to a Certificate of Amendment (the “Certificate of Amendment”) to the Company’s Restated Certificate of Incorporation filed with the Secretary of State of the State of Delaware on December 16, 2022. A copy of the Certificate of Amendment is attached hereto as Exhibit 3.1 and is incorporated herein by reference. This discussion is qualified in its entirety by reference to the full text of the Certificate of Amendment.   As a result of the Reverse Stock Split, every one hundred (100) shares of the Company’s Common Stock issued or outstanding will be automatically reclassified into one share of Common Stock, subject to the treatment of fractional shares as described below, without any action on the part of the holders. Any fractional shares that would otherwise be issuable as a result of the Reverse Stock Split will be rounded up to the nearest whole share. Proportionate adjustments will be made to the conversion and exercise prices and the number of shares underlying the Company’s outstanding equity awards, as applicable, and warrants exercisable for shares of Common Stock, as well as to the number of shares reserved under the Company’s equity incentive plans. The Reverse Stock Split did not affect the number of authorized shares of Common Stock or the par value of the Common Stock. In connection with the Reverse Stock Split, the CUSIP number of the Common Stock will be changed to 829392604. The Common Stock will begin trading on The Nasdaq Capital Market on a reverse split-adjusted basis on December 20, 2022.  January 25, 2016 -- Amedica Corp. (AMDA) will effect a one-for-fifteen (1-15) reverse split of its common stock. In conjunction with the reverse split, the CUSIP number will change to 023435209.