Business: NuCana plc is a clinical-stage biopharmaceutical company focused on significantly improving treatment outcomes for cancer patients by applying its phosphoramidate chemistry technology to transform some of the most widely prescribed chemotherapy agents, nucleoside analogs, into more effective and safer medicines. While these conventional agents remain part of the standard of care for the treatment of many solid tumours, their efficacy is limited by cancer cell resistance mechanisms and they are often poorly tolerated. Utilising the Company's proprietary ProTide technology, they are developing new medicines designed to overcome key cancer resistance mechanisms and generate much higher concentrations of anti-cancer metabolites in cancer cells.